著者所属：Laboratory of Molecular pharmacology, Suntory Institute for Biomedical Research Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University Laboratory of Molecular pharmacology, Suntory Institute for Biomedical Research Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University
Zn2+ at the concentration of 10 μM inhibited the depolarization-induced [3H] glutamate release from the preloaded rat hippocampal slices both in the presence and absence of Ca2+ without affecting [3H] GABA and [3H] Ach release. Of divalent cations tested, Zn2+ and Fe<2+> had an inhibitory effect on the release of glutamate.
