Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Characterization of Capacitation Inhibitory Protein from Rabbit Seminal Plasma : Homology with Human Annexins
岡部 勝岸 雄一郎應 星小濱 靖弘三村 務 /Steven S.-L. LI
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1993 年 16 巻 5 号 p. 453-456

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A protein was purified from rabbit seminal plasma using preparative acrylamide disc electrophoresis, ammonium sulfate precipitation and gel filtration. The protein inhibited the in vitro fertilization of mouse ova inseminated with epididymal sperm and with capacitated sperm. The inhibition was not observed, however, when only ova were exposed to the protein prior to mixing with sperm. The partial protein sequence analysis revealed the strong homology of the rabbit fertilization inhibitory protein to human annexin V.

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© The Pharmaceutical Society of Japan
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