Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
IDENTIFICATION OF N4-(2-PROPENAL) SPERMIDINE AS A MAJOR REACTION PRODUCT OF MALONDIALDEHYDE AND SPERMIDINE
Masaru NIITSUTakeshi OHYAXiaoSong XUKeijiro SAMEJIMA
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JOURNALS FREE ACCESS

1995 Volume 18 Issue 8 Pages 1162-1164

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Abstract

The reactivity of malondialdehyde (MDA) with spermidine at the physiological pH was considerably higher than that with putrescine, glycine, lysine, methylamine or dimethylamine, and the major reaction product of MDA-spermidine adduct was identified as N4-(2-propenal) spermidine.

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© The Pharmaceutical Society of Japan
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