Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Inhibitory Effect of Herbal Medicines on Rotavirus Infectivity
Dong-Hyun KIMMi-Jeong SONGEun-Ah BAEMyung Joo HAN
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2000 年 23 巻 3 号 p. 356-358

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The inhibitory effect of some traditional herbal medicines on the infectivity of rotavirus, which predominanthy occurs in sporadic diarrhea in infants and young children, was investigated. Among the 34 kinds of herbal medicines tested, the fruit of Citrus aurantium had the most potent inhibitory activity on rotavirus infection. The active components of the fruit of Citrus aurantium were neohesperidin and hesperidin. Their 50% inhibitory concentrations were 25 and 10 μM, respectively.
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© The Pharmaceutical Society of Japan
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