抄録
21 cases, diagnosed as meconium ileus or fibrocystic disease of the pancreas in Japan, were reviewed. However, it is very important to decipher whether these cases are typical or not from the view point of the diagnostic criteria presented by di Sant'Agnese. The majority of the cases which were reported as fibrocystic disease of the pancreas in Japan was diagnosed by similar clinical symptoms of fibrocystic disease of the pancreas and histological findings of the pancreas, but with no complete laboratory data. 187 autopsy cases, under 5 years of age, who expired under similar conditions of fatal complication of fibrocystic disease, were examined histologically. Results were as follows: 1. Inspissated material in acini, found by doctors A and B, was in 16.5% and 16.6% of 187 cases respectively. 2. Inspissated material in pancreatic ducts was found in 25.1% and 20.8%. 3. Cystic dilatation of the acini or ducts was found in 9.1% and 8.3%. 4. Fibrosis of the pancreas was seen in 14.4% and 6.7%. Then, it should be emphasized that laboratory data, especially results of the sweat test, are most important in the correct diagnosis of the fibrocystic disease of the pancreas in Japan, because so many autopsy cases, under 5 years of age, showed fibrocystic changes of the pancreas.
