液体クロマトグラフィー/タンデム型質量分析計を用いる河川水中ヘキサメチレンテトラミンの迅速定量

抄録

We developed a simple and fast determination method of hexamethylenetetramine (HMT) by using liquid chromatography/tandem mass spectrometry to evaluate its concentration in river water. Well-defined peaks of HMT were obtained by using a hydrophilic interaction column. A calibration curve showed good linearity (R² = 0.999). The instrumental detection limit and the instrumental quantification limit were 0.06 μg L⁻¹ and 0.16 μg L⁻¹, respectively. Only filtration was adopted for river-water sample pretreatment; the detection limit of HMT was calculated to be 0.12 μg L⁻¹. The recoveries of HMT added to pure water and river water ranged from 102% to 106% and from 92% to 104%. HMT was detected from 6 of 13 grab samples taken from Tone River system between May 18th and May 20th; the maximum concentration was 150 μg L⁻¹.