Effects of 1% Glucose-Containing Ringer's Solution on Intraoperative Plasma Glucose Concentration in Elderly and Young Patients

抄録

The purpose of this study was to evaluate the effects of 1% glucose-containing solution on plasma glucose concentration in elderly and young patients. Twenty-two elderly(>65yr) and 24 young(20-59yr), ASA physical status I or II patients scheduled for elective surgery under general anesthesia were studied. Patients received acetated Ringer's solution containing 1% glucose at a rate of 10ml·kg⁻¹·hr⁻¹. Plasma glucose, sodium and potassium concentrations, and urine volume were measured at just before the incision(baseline), and at 1, 2, and 3 hours(h) after the incision. Plasma glucose concentration in the elderly and the young groups did not change significantly from the baseline values during the 1-3h periods. Plasma glucose at 2h in the young group was significantly lower than that in the elderly group(p<0.05). Incidence of hypoglycemia in the elderly group was significantly lower than that in the young group(p<0.05). Hypoglycemia occurred only in young female patients. 1% glucose-containing solution produced stable intraoperative plasma glucose concentration in the elderly group and the young group except female patients.