Abstract
Aminodeoxykanamycin (Kanendomycin, abbr. AKM) was administered to 68 orthopedical infections in 42 patients. The cases consisted mostly of pyogenic infections of bone and joint, both organs being the most important in the field of orthopedics. The results obtained were as follows.
AKM was administered intramuscularly in the daily dose of 200 mg-400 mg divided into 2 times or once, and it was also applied topically in the wound for the adequate cases. It was proved that the local concentrations of AKM relate closely to the treatment results.
The results obtained were remarkably effective in 28 cases, effective in 23 cases, slightly effective in 12 cases and ineffective in 5 cases.
