生体内における腫瘍細胞の制癌剤に対する感受性試験に関する研究第3報

諸条件下の宿主における制癌剤感受性の差異について

抄録

The sensitivities of anticancer drugs for tumor cell in the hosts with the various conditions were compared.
1) Growth of tumor cell was strongly effected by cellular factor than by humoral factor in host.
2) The grade of sensitivity of anticancer drug for tumor cell showed difference by the conditions of host.
3) Sensitivity of anticancer drug for tumor cell was exactly showed by only humoral factor in host.
4) So, in order to obtain sensitivity of anticancer drug for tumor cell, the test must be investigated in vivo. And tumor cell must not be strongly influenced by host. Therefore the diffusion chamber technique is useful as sensitivity test of anticancer drug for tumor cell.