Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
Clinical Investigation
Assessment of Coronary Intima - Media Thickness by Optical Coherence Tomography
Comparison With Intravascular Ultrasound
Teruyoshi KumeTakashi AkasakaTakahiro KawamotoNozomi WatanabeEiji ToyotaYoji NeishiRenan SukmawanYoshito SadahiraKiyoshi Yoshida
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2005 Volume 69 Issue 8 Pages 903-907

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Abstract

Background Optical coherence tomography (OCT) is a new imaging method. With a resolution of approximately 10-20 Ém, which is approximately 10-fold higher than that of intravascular ultrasound (IVUS). Methods and Results This study compared the coronary intima - media thickness (IMT) and the intimal thickness of 54 coronary arterial segments evaluated by histological examination with the results of OCT and IVUS. There was better agreement in IMT between OCT and histological examination than between IVUS and histological examination (r=0.95, p<0.001, mean difference =-0.01±0.07 mm for OCT; r=0.88, p<0.001, mean difference =-0.03±0.10 mm for IVUS). There was good agreement in the intimal thickness between OCT and histological examination (r=0.98, p<0.001, mean difference =0.01±0.04 mm). Conclusions IMT could be measured more accurately by OCT than IVUS. In addition, the intimal thickness could be evaluated by OCT and correlated well with the histological examination. (Circ J 2005; 69: 903 - 907)

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© 2005 THE JAPANESE CIRCULATION SOCIETY
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