Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
Clinical Investigation
Availability of Cardio-Ankle Vascular Index (CAVI) as a Screening Tool for Atherosclerosis
Koichiro KadotaNoboru TakamuraKiyoshi AoyagiHironori YamasakiToshiro UsaMio NakazatoTakahiro MaedaMitsuhiro WadaKen-ichiro NakashimaKoh AbeFuminao TakeshimaYoshiyuki Ozono
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2008 Volume 72 Issue 2 Pages 304-308

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Abstract

Background A novel index, the cardio-ankle vascular index (CAVI), which reflects the stiffness of the aorta, femoral artery, and tibial artery, was recently developed by measuring brachial - ankle pulse wave velocity and blood pressure. Methods and Results In the present study 1,014 Japanese adults from the general population were screened to clarify the correlation between CAVI and other existing markers related to atherosclerosis, including carotid intima - media thickness (CIMT) and homocysteine (HCY). CAVI was strongly associated with age in both men and women. After adjustment for age and sex, CAVI was correlated with systolic and diastolic blood pressures. In addition, CAVI was significantly correlated with total cholesterol hemoglobin A1c and total HCY, as well as CIMT. Conclusion CAVI is an appropriate screening tool for atherosclerosis, but further studies are needed to establish a convenient and effective screening system using it. (Circ J 2008; 72: 304 - 308)

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© 2008 THE JAPANESE CIRCULATION SOCIETY
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