Circulation Journal
Case Report
Infliximab Treatment for Refractory Kawasaki Disease With Coronary Artery Aneurysm
A 1-Month-Old Girl
Taku OishiMikiya FujiedaTaisuke ShiraishiMiki OnoKazuo InoueAkiyoshi TakahashiHideo OguraHiroshi Wakiguchi
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Volume 72 (2008) Issue 5 Pages 850-852

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Abstract

Tumor necrosis factor-α (TNF-α) is considered to be 1 of the factors that induce vasculitis, including coronary artery aneurysm (CA), in Kawasaki disease (KD), because the blood concentration of TNF-α is higher in patients with CA compared with those without. Therefore, an anti-TNF-αagent (infliximab) was administered to a 1-month-old girl with refractory KD complicated by CA and subsequently, the CA improved and KD was controlled without complications 20 months after the onset. (Circ J 2008; 72: 850 - 852)

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© 2008 THE JAPANESE CIRCULATION SOCIETY
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