Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
Rapid Communication
Double-Blind and Placebo-Controlled Study of the Effectiveness and Safety of Extracorporeal Cardiac Shock Wave Therapy for Severe Angina Pectoris
Yoku KikuchiKenta ItoYoshitaka ItoTakashi ShirotoRyuji TsuburayaKentaro AizawaKiyotaka HaoYoshihiro FukumotoJun TakahashiMorihiko TakedaMasaharu NakayamaSatoshi YasudaShinichi KuriyamaIchiro TsujiHiroaki Shimokawa
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2010 Volume 74 Issue 3 Pages 589-591

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Abstract

Background: Low-energy shock wave (SW) therapy has improved myocardial ischemia in both a porcine model and in patients with severe angina pectoris. Methods and Results: To further confirm the effectiveness and safety of SW therapy, 8 patients with severe angina pectoris were treated with SW therapy in a double-blind, placebo-controlled and cross-over manner. SW therapy, but not placebo, significantly improved chest pain symptoms and cardiac function without any complications or adverse effects. Conclusions: Extracorporeal cardiac SW therapy is an effective, safe and non-invasive therapeutic option for severe angina pectoris. (Circ J 2010; 74: 589 - 591)

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© 2010 THE JAPANESE CIRCULATION SOCIETY
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