Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
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Increased Coronary Perivascular Adipose Tissue Volume in Patients With Vasospastic Angina
Kazuma Ohyama, Yasuharu Matsumoto, Kensuke Nishimiya, Kiyotaka Hao, Ryuji Tsuburaya, Hideki Ota, Hirokazu Amamizu, Hironori Uzuka, Jun Takahashi, Kenta Ito, Hiroaki Shimokawa
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Keywords: Adipose tissue, Computed tomography, Coronary spasm
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2016 Volume 80 Issue 7 Pages 1653-1656

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Abstract
Background:Recent studies have suggested that coronary perivascular adipose tissue (PVAT) impairs coronary vasomotion, so we examined whether PVAT is increased at the spastic coronary segment in patients with vasospastic angina (VSA).Methods and Results:PVAT volume in the left anterior descending (LAD) coronary arteries on CT coronary angiography was significantly increased in 48 VSA patients with LAD spasm compared with 18 controls (30.7±2.0 vs. 21.0±3.2 cm3, P=0.01), whereas that of total epicardial adipose tissue was comparable between the 2 groups.Conclusions:The results suggested an important role of PVAT in the pathogenesis of coronary spasm. (Circ J 2016; 80: 1653–1656)
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© 2016 THE JAPANESE CIRCULATION SOCIETY
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The Nippon Journal of Clinical Angio-Cardiology

Japanese Circulation Journal

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