Comparative Study of Arteriosclerosis between Brain and Heart, with Special Reference to the Cerebrovascular and Coronary Heart Disease

Abstract

The present study was undertaken to define the etiologic mechanism of CVD and coronary heart disease and to detect their relation. In a series of 328 autopsies (37 cases of cerebral hemorrhage, 60 of cerebral infarction, 51 of myocardial infarction and 180 of miscellaneous disease), macroscopic and microscopic studies of intracerebral arteries, cerebral basilar arteries and coronary arteries were carried out. Generally, intracerebral arterial lesions had no relation with atherosclerosis, but in the atherosclerotic lesions between brain and heart close correlation was noted in individual cases. From these results some consideration to the pathogenesis of vascular lesions in CVD and coronary heart disease was conducted.