Baseline Prolonged QRS Duration May Predict In-Hospital Outcomes of Patients With Acute Myocarditis　― Multicenter Observational Study ―

Ayano Yoshida; Takuma Takada; Eiji Shibahashi; Takuro Abe; Kensuke Shimazaki; Takanori Kawamoto; Motoko Kametani; Natsuko Satomi; Kazuho Kamishima; Takashi Saito; Erina Tomari; Atsushi Honda; Atsushi Takagi; Kyomi Ashihara; Junichi Yamaguchi; Kentaro Jujo

doi:10.1253/circrep.CR-25-0306

Research Letters

Baseline Prolonged QRS Duration May Predict In-Hospital Outcomes of Patients With Acute Myocarditis　― Multicenter Observational Study ―

Ayano Yoshida, Takuma Takada , Eiji Shibahashi, Takuro Abe, Kensuke Shimazaki, Takanori Kawamoto, Motoko Kametani, Natsuko Satomi, Kazuho Kamishima, Takashi Saito, Erina Tomari, Atsushi Honda, Atsushi Takagi, Kyomi Ashihara, Junichi Yamaguchi, Kentaro Jujo

Author information

Ayano Yoshida
Department of Cardiology, Tokyo Women’s Medical University [Japan]
Takuma Takada Corresponding author
Department of Cardiology, Tokyo Women’s Medical University [Japan]
Institute of Advanced Biomedical Engineering and Science, Tokyo Women’s Medical University [Japan]
Eiji Shibahashi
Department of Cardiology, Tokyo Women’s Medical University Medical Center East [Japan]
Takuro Abe
Department of Cardiology, Nishiarai Heart Center Hospital [Japan]
Kensuke Shimazaki
Department of Cardiology, Nishiarai Heart Center Hospital [Japan]
Takanori Kawamoto
Department of Cardiology, Seirei Hamamatsu General Hospital [Japan]
Motoko Kametani
Department of Cardiology, Saiseikai Kumamoto Hospital [Japan]
Natsuko Satomi
Department of Cardiology, Ogikubo Hospital [Japan]
Kazuho Kamishima
Department of Cardiology, Kosei Hospital [Japan]
Takashi Saito
Department of Cardiology, National Hospital Organization Yokohama Medical Center [Japan]
Erina Tomari
Department of Cardiology, Tokyo Women’s Medical University Yachiyo Medical Center [Japan]
Atsushi Honda
Department of Cardiology, Tokyo Women’s Medical University Yachiyo Medical Center [Japan]
Atsushi Takagi
Department of Cardiology, Saiseikai Kawaguchi General Hospital [Japan]
Kyomi Ashihara
Department of Cardiology, Tokyo Women’s Medical University [Japan]
Junichi Yamaguchi
Department of Cardiology, Tokyo Women’s Medical University [Japan]
Kentaro Jujo Corresponding author
Department of Cardiology, Tokyo Women’s Medical University Medical Center East [Japan]
Department of Cardiology, Saitama Medical University, Saitama Medical Center [Japan]

Keywords: Acute myocarditis, Electrocardiogram, In-hospital prognosis, Risk factor

JOURNAL OPEN ACCESS FULL-TEXT HTML

2026 Volume 8 Issue 4 Pages 674-676

DOI https://doi.org/10.1253/circrep.CR-25-0306

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Abstract

Background: The prognosis of acute myocarditis (AM) is difficult to predict due to its variable presentation. We investigated the prognosticators of AM patients requiring hospitalization.

Methods and Results: We conducted a multicenter observational study including 80 hospitalized AM patients. The primary endpoint was a composite of all-cause death, heart transplantation, and implantation of ventricular assist devices during the index hospitalization. Thirteen (16%) patients reached the endpoint. Longer QRS duration at admission independently predicted adverse outcomes, with an optimal cut-off of 130 ms.

Conclusions: Prolonged QRS duration at admission might predict in-hospital prognosis in AM patients regardless of whether or not it was fulminant.

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