2026 Volume 8 Issue 6 Pages 1011-1012
Background: Conventional lung perfusion scintigraphy relies on relative tracer distribution and has limited utility for longitudinal assessment of regional pulmonary perfusion in chronic thromboembolic pulmonary hypertension (CTEPH).
Methods and Results: We applied CT-derived, lung volume–normalized standardized uptake value (SUVLV)-based 3-color SPECT/CT mapping in a patient with CTEPH undergoing staged balloon pulmonary angioplasty followed by pulmonary endarterectomy. This approach visualized regional perfusion redistribution and vascular steal patterns not clearly identified by conventional SPECT/CT and demonstrated close spatial concordance with pulmonary angiographic findings throughout multimodal treatment.
Conclusions: SUVLV-normalized 3-color SPECT/CT enables intuitive visualization of dynamic pulmonary perfusion redistribution during staged interventions.