Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Two Triterpene Saponins from Achyranthes bidentata
Anne-Claire MITAINE-OFFERAbderrazak MAROUFBernard HANQUETNicolas BIRLIRAKISMarie-Aleth LACAILLE-DUBOIS
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2001 年 49 巻 11 号 p. 1492-1494

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Bidentatoside II (1) and chikusetsusaponin V methyl ester (2) are two further triterpene saponins isolated from the roots of Achyranthes bidentata. Chemical and homo and heteronuclear two-dimensional (2D) NMR techniques have led to the structural elucidation of 1 which is a new seco-glycoside of oleanolic acid and the full 1H- and 13C-NMR assignments of 2. These compounds did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.

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© 2001 The Pharmaceutical Society of Japan
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