The Biosynthesis of Broussonetines: Origin of the Carbon Skeleton

Makio SHIBANO; Daisuke TSUKAMOTO; Takae INOUE; Yoko TAKASE; Genjiro KUSANO

doi:10.1248/cpb.49.504

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The Biosynthesis of Broussonetines: Origin of the Carbon Skeleton

Makio SHIBANO, Daisuke TSUKAMOTO, Takae INOUE, Yoko TAKASE, Genjiro KUSANO

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Keywords: biosynthesis, Broussonetia kazinoki, broussonetine J, broussonetine C, broussonetine E

JOURNAL FREE ACCESS

2001 Volume 49 Issue 4 Pages 504-506

DOI https://doi.org/10.1248/cpb.49.504

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Abstract

Broussonetines are glycosidase-inhibitory alkaloids obtained from Broussonetia kazinoki. Feeding experiments using [1-¹³C]glucose and ¹³C-NMR spectroscopic studies showed that broussonetines are biosynthesized through routes similar to those of sphingosine and phytosphingosine.

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