Medicinal Foodstuffs. XXV. Hepatoprotective Principle and Structures of Ionone Glucoside, Phenethyl Glycoside, and Flavonol Oligoglycosides from Young Seedpods of Garden Peas, Pisum sativum L.

抄録

A new ionone glucoside, pisumionoside, a phenethyl glycoside, sayaendoside, and two acylated flavonol oligoglycosides, pisumflavonosides I and II, were isolated from the young seedpods of garden peas, Pisum sativum L., together with quercetin and kaempferol 3-O-(6-O-trans-p-coumaroyl)-β-D-glucopyranosyl (1→2)-β-D-glucopyranosyl (1→2)-β-D-glucopyranosides and quercetin and kaempferol 3-sophorotriosides. The structures of pisumionoside, sayaendoside, and pisumflavonosides I and II were determined on the basis of chemical and physicochemical evidence, respectively. Quercetin 3-sophorotrioside, a principle component, was found to show protective effects on liver injury induced by D-galactosamine and lipopolysaccharide and by carbon tetrachloride in mice.