α-Glucosidase Inhibitory Constituents from Cuscuta reflexa

Abstract

Two new compounds, 7′-(3′, 4′-dihydroxyphenyl)-N-[(4-methoxyphenyl)ethyl]propenamide (4), and 7′-(4′-hydroxy, 3′-methoxyphenyl)-N-[(4-butylphenyl)ethyl]propenamide (5) have been isolated from Cuscuta reflexa along with five known compounds, 6, 7-dimethoxy-2H-1-benzopyran-2-one (1), 3-(3, 4-dihydroxyphenyl)-2-propen-1-ethanoate (2), 6, 7, 8-trimethoxy-2H-1-benzopyran-2-one (3), 3-(4-O-β-d-glucopyranoside-3, 5-dimethoxyphenyl)-2-propen-1-ol (6), 2-(3-hydroxy-4-methoxyphenyl)-3, 5-dihydroxy-7-O-β-d-glucopyranoside-4H-1-benzopyrane-4-one (7), reported for the first time from this species. Structures of these compounds were determined by spectral analysis. These compounds showed strong inhibitory activity against α-glucosidase.