Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Cycloartane Glycosides from the Rhizomes of Cimicifuga racemosa and Their Cytotoxic Activities
Kazuki WatanabeYoshihiro MimakiHiroshi SakagamiYutaka Sashida
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2002 年 50 巻 1 号 p. 121-125

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Phytochemical analysis of the rhizomes of Cimicifuga racemosa (Ranunculaceae) resulted in the isolation of twelve cycloartane glycosides (1—12), including four new ones (4—6, 12). The structures of the new compounds were determined by spectroscopic analysis, including two-dimensional (2D) NMR data, and chemical methods. The isolated compounds were evaluated for their cytotoxic activities against human oral squamous cell carcinoma (HSC-2) cells and normal human gingival fibroblasts (HGF).
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© 2002 The Pharmaceutical Society of Japan
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