A New Method for Synthesis of 7-Deoxytaxane Analogues by Hydrogenation of Δ6,7-Taxane Derivatives

Yasuyuki Takeda; Toshiharu Yoshino; Kouichi Uoto; Hirofumi Terasawa; Tsunehiko Soga

doi:10.1248/cpb.50.1398

Notes

A New Method for Synthesis of 7-Deoxytaxane Analogues by Hydrogenation of Δ^6,7-Taxane Derivatives

Yasuyuki Takeda, Toshiharu Yoshino, Kouichi Uoto, Hirofumi Terasawa, Tsunehiko Soga

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Keywords: 7-deoxytaxane analogue, hydrogenation, new efficient method

JOURNAL FREE ACCESS

2002 Volume 50 Issue 10 Pages 1398-1400

DOI https://doi.org/10.1248/cpb.50.1398

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Abstract

A new method for the synthesis of 7-deoxytaxane analogues has been established through hydrogenation of Δ^6,7-taxane derivatives. Among several catalysts examined, Pd–C was found to be a most effective catalyst for the preparation of target compound.

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