Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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New Phenylethanoid Glycosides from Veronica pectinata var. glandulosa and Their Free Radical Scavenging Activities
Iclal SaracogluUmmuhan Sebnem HarputMakoto InoueYukio Ogihara
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2002 Volume 50 Issue 5 Pages 665-668

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Abstract
A known phenylethanoid glycoside, ehrenoside (1), was isolated together with three new phenylethanoid glycosides, verpectoside A (2), B (3) and C (4) from the aerial parts of Veronica pectinata var. glandulosa. On the basis of spectral analysis (UV, FAB-MS, 1H-, 13C- and 2D-NMR), compounds 2—4 were determined to be 2-(3,4-dihydroxyphenyl)ethyl-O-α-L-arabinopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→3)]-(4-O-trans-feruloyl)-β-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl-O-β-D-glucopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→3)]-(4-O-trans-caffeoyl)-β-D-glucopyranoside and 2-(3,4-dihydroxyphenyl)ethyl-O-β-D-glucopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→3)]-(4-O-trans-feruloyl)-β-D-glucopyranoside, respectively. Isolated phenylethanoid glycosides exhibited potent radical scavenging activity against the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
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© 2002 The Pharmaceutical Society of Japan
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