Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
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Eurycomaoside: A New Quassinoid-Type Glycoside from the Roots of Eurycoma longifolia
Erdal BedirHassan Abou-GazarJulius Ngunde NgwendsonIkhlas Ahmad Khan
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Volume 51 (2003) Issue 11 Pages 1301-1303

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Abstract

A new C19-quassinoid-type glycoside has been isolated from the roots of Eurycoma longifolia. The structure elucidation of the compound was achieved by a combination of one- and two-dimensional NMR techniques, including 1H–1H-correlation spectroscopy (COSY), 1H–13C-heteronuclear correlation spectroscopy (HMQC), and 1H–13C-heteronuclear multiple-bond correlation spectroscopy (HMBC), as well as high resolution electrospray ionization Fourier transformation mass spectrometry (HR-ESI-FT-MS) data. The C(1)-glycosidation site in the quassinoid framework is encountered for the first time.

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© 2003 The Pharmaceutical Society of Japan
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