Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Studies on the Constituents of Leonurus sibiricus L.
Mitsuru SatohYoshio SatohKimiaki IsobeYasuo Fujimoto
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2003 Volume 51 Issue 3 Pages 341-342

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Abstract
Two new furanoditerpene-lactones, LS-1 (1) and LS-2 (2), were isolated along with four known furanoditerpene-lactones 3, 4, 5 and 6 from the aerial part of Leonurus sibiricus L. The structures of the new compounds were determined by spectroscopic means. Compounds 1—6 isolated here exhibited moderate cytotoxic activity (IC50=50—60 μg/ml) against leukemia cells (L 1210) in tissue culture.
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© 2003 The Pharmaceutical Society of Japan
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