Development of a Novel Compression Tester and Rheo-Mechanical Properties of Wet-Mass Powder. II
—Effect of Moisture Content on the Rheo-Mechanical Properties—

Abstract

In our previous paper [Watano S., et al., Chem. Pharm. Bull., 51(7), 747—750 (2003)], a novel compression tester, which enables the vertical and radial pressure transmission measurement, has been developed and quantitative analysis of rheo-mechanical properties of wet-mass powder prepared by different kneading times was conducted. In this study, the compression test was conducted by using the kneaded wet-mass powders prepared by different moisture contents. Pressure transmission characteristics and rheo-mechanical properties have been investigated to characterize the wet-mass powders. The relationship between these parameters and granule physical properties was also investigated.