Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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A Simple and Highly Practical Oxidation of Primary Alcohols to Acids Mediated by 2,2,6,6-Tetramethyl-1-piperidinyloxy (TEMPO)
Atsuhiko Zanka
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Keywords: 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO), oxidation, alcohol, acid, one-pot
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2003 Volume 51 Issue 7 Pages 888-889

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Abstract
Primary alcohols were quantitatively oxidized in one-pot to acids via 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) mediated oxidation. The reported method is simple and suitable for large scale synthesis.
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© 2003 The Pharmaceutical Society of Japan
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