Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
A New Iridoid Glycoside with Nerve Growth Factor-Potentiating Activity, Gelsemiol 6′-trans-Caffeoyl-1-glucoside, from Verbena littoralis
Yushan LiMasami IshibashiMasayuki SatakeYasukatsu OshimaYasushi Ohizumi
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2003 年 51 巻 9 号 p. 1103-1105

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A new iridoid glycoside, gelsemiol 6′-trans-caffeoyl-1-glucoside (1), was isolated from Verbena littoralis, together with four known phenylethanoid glycosides, acteoside (2), 2′-acetylacteoside (3), jionoside (4), and isoverbascoside (5). Their structures were elucidated by spectral data. Compound 1 showed weak enhancement of nerve growth factor (NGF)-mediated neurite outgrowth from PC12D cells.

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© 2003 The Pharmaceutical Society of Japan
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