Antimicrobial Screening and Quantitative Determination of Benzoic Acid Derivative of Gomphrena celosioides by TLC-Densitometry

Rute Mendonça Xavier de Moura; Paulo Sérgio Pereira; Ana Helena Januário; Suzelei de Castro França; Diones Aparecida Dias

doi:10.1248/cpb.52.1342

Notes

Antimicrobial Screening and Quantitative Determination of Benzoic Acid Derivative of Gomphrena celosioides by TLC-Densitometry

Rute Mendonça Xavier de Moura, Paulo Sérgio Pereira, Ana Helena Januário, Suzelei de Castro França, Diones Aparecida Dias

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Keywords: Gomphrena celosioides, Amaranthaceae, antimicrobial activity, 4-hydroxy-3-methoxy-benzoic acid, TLC-densitometry

JOURNAL FREE ACCESS

2004 Volume 52 Issue 11 Pages 1342-1344

DOI https://doi.org/10.1248/cpb.52.1342

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Abstract

The antimicrobial activity of ethanolic extract and pure compounds of Gomphrena celosioides have been screened by Kirby–Bauer method. Quantitative determination of 4-hydroxy-3-methoxy-benzoic acid in stems, leaves, flowers and roots was established by TLC-densitometry. Results showed significant activity against Staphylococcus aureus and Salmonella typhi. There were no significant differences in the determined benzoic acid derivative.

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