Synthesis of 2-N,N-Dimethylaminomethyl-2,3,3a,12b-tetrahydrodibenzo-[b,f]furo[2,3-d]oxepin Derivatives as Potential Anxiolytic Agents

Andrés Avelino Trabanco; José Manuel Alonso; José Ignacio Andrés; José Maria Cid; Javier Fernández; Laura Iturrino; Anton Megens

doi:10.1248/cpb.52.262

Notes

Synthesis of 2-N,N-Dimethylaminomethyl-2,3,3a,12b-tetrahydrodibenzo-[b,f]furo[2,3-d]oxepin Derivatives as Potential Anxiolytic Agents

Andrés Avelino Trabanco, José Manuel Alonso, José Ignacio Andrés, José Maria Cid, Javier Fernández, Laura Iturrino, Anton Megens

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Keywords: anxiolytic, tetrahydrofuran, dibenzoxepin, heterocyclic compound

JOURNAL FREE ACCESS

2004 Volume 52 Issue 2 Pages 262-265

DOI https://doi.org/10.1248/cpb.52.262

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Abstract

New synthesis approaches that have led to a series of novel tetrahydrodibenzo[b,f]furo[2,3-d]oxepin derivatives are described. According to preliminary data these novel tetracycles can be useful intermediates for the preparation of potential new therapeutic agents.

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