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Chemical and Pharmaceutical Bulletin
Vol. 52 (2004) No. 4 P 454-455




A new compound, nigeglanine (1), and its new artificial derivative (1a), were isolated from the seeds of Nigella glandulifera, together with a known aporphine alkaloid, fuzitine (2). Their structures were established by spectral analysis, including two-dimensional (2D)-NMR spectroscopy. Nigeglanine (1) is the third natural product determined to contain an indazole nucleus.

Copyright © 2004 The Pharmaceutical Society of Japan

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