Nine Regioisomeric and Stereoisomeric Triterpene Dimers from Maytenus chuchuhuasca

Abstract

Nine regioisomeric and stereoisomeric triterpene dimers, namely xuxuarine Fα (1), isoxuxuarine Fα (2; cangorosin B), 7,8-dihydroisoxuxuarine Fα (3), isoxuxuarine Gβ (4), 7,8-dihydroisoxuxuarine Gα (5), isoxuxuarine Eβ (6), 7α-hydroxyisoxuxuarine Eα (7), 7′,8′-dihydroxuxuarine Aα (8), and 7′,8′-dihydroxuxuarine Dβ (9), were isolated from the Brazilian medicinal plant “xuxuá” (Maytenus chuchuhuasca). Their structures have been elucidated based on several spectroscopic analyses including 2D-NMR experiments, MS spectra and CD spectral studies.