Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
(+)-Bornyl Piperate, a New Monoterpene Ester from Piper aff. pedicellatum Roots
Thitima RukachaisirikulSamran PrabpaiPalangpon KongsaereeApichart Suksamrarn
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2004 年 52 巻 6 号 p. 760-761

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A new monoterpene ester, (+)-bornyl piperate was isolated from the underground roots of Piper aff. pedicellatum and its structure was elucidated on the basis of spectroscopic evidence and confirmed by X-ray analysis. The compound crystallizes in the triclinic space group P1 with a=7.3232(4) Å, b=11.4705(7) Å, c=23.2520(14) Å, V=1943.6(2) Å3. This compound showed an antituberculosis activity against Mycobacterium tuberculosis (H37Ra strain) with the minimum inhibitor concentration (MIC) of 25 μg/ml.

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© 2004 The Pharmaceutical Society of Japan
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