Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
N-Phenylphthalimide-Type Cyclooxygenase (COX) Inhibitors Derived from Thalidomide: Substituent Effects on Subtype Selectivity
Hiroko SanoTomomi NoguchiAya TanataniHiroyuki MiyachiYuichi Hashimoto
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2004 年 52 巻 8 号 p. 1021-1022

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Several N-substituted phenylphthalimide and phenylhomophthalimide derivatives with cyclooxygenase (COX)-inhibitory activity were prepared during structural development studies based on thalidomide as a lead compound. Substituent effects on the subtype selectivity were investigated.

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© 2004 The Pharmaceutical Society of Japan
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