Examination of the Reactivity of Hydroxy Groups in Multioxygenated Cyclohexanoids: Synthetic Study toward Cytotoxic Pericosine B

Abstract

The reactivity of two hydroxy groups in some multioxygenated cyclohexanoids was examined for basic study of the synthesis of the cytotoxic marine natural product pericosine B and related compounds. Differences in reactivity for O-methylation or O-acylation among substrates were observed.