Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
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Constituents from the Stems of Hibiscus taiwanensis
Pei-Lin WuTian-Shung WuCai-Xia HeChia-Hao SuKuo-Hsiung Lee
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2005 Volume 53 Issue 1 Pages 56-59

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Abstract

Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(−)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

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© 2005 The Pharmaceutical Society of Japan
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