Compounds Structurally Related to Tamoxifen as Openers of Large-Conductance Calcium-Activated K+ Channel

Yu Sha; Toshihiko Tashima; Yumi Mochizuki; Yoshimi Toriumi; Satomi Adachi-Akahane; Taro Nonomura; Maosheng Cheng; Tomohiko Ohwada

doi:10.1248/cpb.53.1372

Communications to the Editor

Compounds Structurally Related to Tamoxifen as Openers of Large-Conductance Calcium-Activated K⁺ Channel

Yu Sha, Toshihiko Tashima, Yumi Mochizuki, Yoshimi Toriumi, Satomi Adachi-Akahane, Taro Nonomura, Maosheng Cheng, Tomohiko Ohwada

著者情報

キーワード: large-conductance calcium-activated K⁺ channel, tamoxifen, channel opener, (xeno)estrogen, electrophysiology

ジャーナルフリー

2005 年 53 巻 10 号 p. 1372-1373

DOI https://doi.org/10.1248/cpb.53.1372

詳細

抄録

We found that a variety of compounds containing partial structures of tamoxifen showed activity as chemical modulators of large-conductance calcium-activated K⁺ channels (BK channels).

責任著者(Corresponding author)

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