Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Three New Podocarpane-Type Diterpenoids from Callus of Securinega suffruticosa
Wei YuanZiming LuYing LiuChao MengKe-di ChengPing Zhu
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2005 年 53 巻 12 号 p. 1610-1612

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Three new podocarpane-type diterpenoids, 3β,12-dihydroxy-13-methyl-6,8,11,13-podocarpatetraen (1), 3β,12-dihydroxy-13-methyl-5,8,11,13-podocarpatetraen-7-one (2), and 1-(7-hydroxy-2,6-dimethyl-1-naphthyl)-4-methyl-3-pentanone (3) (20(10→5)-abeo-4,5-seco-5(10),6,8,11,13-podocarpapentaen-3-one) were isolated from callus of Securinega suffruticosa. The structures were elucidated by spectroscopic methods. Compounds 1, 2, and 3 showed cytotoxic activity against five human cancer cell lines (A549, BEL 7402, BGC-823, HCT-8, A2780).
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© 2005 The Pharmaceutical Society of Japan
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