J-STAGE Home  >  Publications - Top  > Bibliographic Information

Chemical and Pharmaceutical Bulletin
Vol. 53 (2005) No. 2 P 229-231




A new 4α-aryltetralin-type lignan called burseranin (1) and a known analogous lignan picropolygamain (2) were isolated along with known triterpenes, lupeol and epi-lupeol from the methanol extract of stems of Bursera graveolens, which showed a remarkable inhibitory activity against human HT1080 fibrosarcoma cells. The whole structure of 1 was established based on combined spectral studies and the absolute structure for 2 was first confirmed by CD spectral evidence. In addition, cytotoxic activities of the stem (methanol) extract and its components are evaluated in this paper.

Copyright © 2005 The Pharmaceutical Society of Japan

Article Tools

Share this Article