Staphylionosides A—K: Megastigmane Glucosides from the Leaves of Staphylea bumalda DC.

Abstract

Chemical investigation of leaves of Staphylea bumalda DC., collected in the suburbs of Hiroshima City, afforded 11 new megastigmane glucosides, named staphylionosides A—K (3—13), along with two known megastigmane glucosides (1, 2). The relative structures were elucidated from spectroscopic evidence, and the absolute structures of the aglycones were determined by means of the combination of β-D-glucosylation-induced shift-trends and the modified Mosher's method.