Microbial Transformation of Mestranol by Cunninghamella elegans

Muhammad Iqbal Choudhary; Syed Ghulam Musharraf; Zafar Ali Siddiqui; Naik Tameen Khan; Rahat Azhar Ali; Atta-ur-Rahman

doi:10.1248/cpb.53.1011

Notes

Microbial Transformation of Mestranol by Cunninghamella elegans

Muhammad Iqbal Choudhary, Syed Ghulam Musharraf, Zafar Ali Siddiqui, Naik Tameen Khan, Rahat Azhar Ali, Atta-ur-Rahman

著者情報

キーワード: mestranol, 17β-methoxymestranol, microbial transformation, Cunninghamella elegans

ジャーナルフリー

2005 年 53 巻 8 号 p. 1011-1013

DOI https://doi.org/10.1248/cpb.53.1011

詳細

抄録

The microbial transformation of an oral contraceptive, mestranol (1) by Cunninghamella elegans yielded two hydroxylated metabolites, 6β-hydroxymestranol (2) and 6β,12β-dihydroxymestranol (3). Metabolite 3 was found to be a new compound. These metabolites were structurally characterized on the basis of spectroscopic techniques.

責任著者(Corresponding author)

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