Isolation and Characterization of 1,3-Dicapryloyl-2-linoleoylglycerol: A Novel Triglyceride from Berries of Hippophae rhamnoides

Anand Swaroop; Arun Kumar Sinha; Raman Chawla; Rajesh Arora; Rakesh Kumar Sharma; Jonala Kotesh Kumar

doi:10.1248/cpb.53.1021

Notes

Isolation and Characterization of 1,3-Dicapryloyl-2-linoleoylglycerol: A Novel Triglyceride from Berries of Hippophae rhamnoides

Anand Swaroop, Arun Kumar Sinha, Raman Chawla, Rajesh Arora, Rakesh Kumar Sharma, Jonala Kotesh Kumar

著者情報

キーワード: Hippophae rhamnoides, Elaeagnaceae, 1,3-dicapryloyl-2-linoleoylglycerol, metal chelation, free radical scavenging, lipid peroxidation

ジャーナルフリー

2005 年 53 巻 8 号 p. 1021-1024

DOI https://doi.org/10.1248/cpb.53.1021

詳細

抄録

1,3-Dicapryloyl-2-linoleoylglycerol (1), a novel triglyceride, was isolated from berries of Hippophae rhamnoides. The structure was elucidated on the basis of MS, 1D and 2D NMR experiments including HMQC and HMBC. The metal chelating, free radical scavenging, and lipid peroxidation inhibiting properties of the compound were also estimated with particular reference to radiation protection. In case of metal chelation and superoxide ion scavenging, 1 showed maximum inhibition at 50 μg/ml (11%) and 100 μg/ml (55%), respectively, whereas in lipid peroxidation, 1 showed maximum inhibition (57%) at 2 mg/ml as compared to quercetin as a control.

責任著者(Corresponding author)

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