Synthesis, Characterisation and Biological Evaluation of Lanthanide(III) Complexes with 3-Acetylcoumarin-o-aminobenzoylhydrazone (ACAB)

Abstract

Lanthanide(III) complexes of the general formula [Ln(ACAB)₂(NO₃)₂(H₂O)₂]·NO₃·H₂O where Ln=La(III), Pr(III), Nd(III), Sm(III), Eu(III), Gd(III), Tb(III), Dy(III) and Y(III), ACAB=3-acetylcoumarin-o-aminobenzoylhydrazone have been isolated and characterised based on elemental analyses, molar conductance, IR, ¹H- and ¹³C-NMR, UV, TG/DTA and EPR spectral studies. The ligand behaves in bidentate fashion coordinating through hydrazide >C=O and nitrogen of >C=N. A coordination number of ten is assigned to the complexes. Antibacterial and Antifungal studies indicate an enhancement of activity of the ligand on complexation.