Jaspolides A—F, Six New Isomalabricane-Type Terpenoids from the Sponge Jaspis sp.

Shengan Tang; Yuehu Pei; Hongzheng Fu; Zhiwei Deng; Jun Li; Peter Proksch; Wenhan Lin

doi:10.1248/cpb.54.4

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Jaspolides A—F, Six New Isomalabricane-Type Terpenoids from the Sponge Jaspis sp.

Shengan Tang, Yuehu Pei, Hongzheng Fu, Zhiwei Deng, Jun Li, Peter Proksch, Wenhan Lin

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Keywords: marine sponge, Jaspis sp., isomalabaricanes, terpenoids, structural elucidation

JOURNAL FREE ACCESS

2006 Volume 54 Issue 1 Pages 4-8

DOI https://doi.org/10.1248/cpb.54.4

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Abstract

A chemical investigation of Jaspis sp., the marine sponge collected from the South China Sea led to the isolation of six new isomalabaricane-type compounds, jaspolides A—F (1—6). The structures of those compounds were elucidated by extensive spectroscopic methods. The structure-types of 1 to 6 could be classified into triterpenes (1, 2), sesterterpene (6), diterpenes (3, 4), and nortriterpene (5). The biogenetic transformation of the isolated compounds was also speculated.

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