Xylogranatins A—D, New Mexicanolides from the Fruit of a Chinese Mangrove Xylocarpus granatum

Abstract

Four new mexicanolides with a Δ^14,15 double bond, named xylogranatins A and D (1—4), were isolated from the fruit of a Chinese mangrove Xylocarpus granatum, together with two known 8,9,30-phragmalin ortho esters, xyloccensins P and Q. Their structures were elucidated on the basis of spectroscopic data, especially 2D NMR techniques including HSQC, HMBC and NOESY.