Larvicidal, Antimycobacterial and Antifungal Compounds from the Bark of the Peruvian Plant Swartzia polyphylla DC

Rosario Rojas; Betty Bustamante; Palmira Ventosilla; Irma Fernádez; Luz Caviedes; Robert Henry Gilman; Olga Lock; Gerald Bruce Hammond

doi:10.1248/cpb.54.278

Notes

Larvicidal, Antimycobacterial and Antifungal Compounds from the Bark of the Peruvian Plant Swartzia polyphylla DC

Rosario Rojas, Betty Bustamante, Palmira Ventosilla, Irma Fernádez, Luz Caviedes, Robert Henry Gilman, Olga Lock, Gerald Bruce Hammond

Author information

Keywords: antimycobacterial, antifungal, biochanin A, dihydrobiochanin A, larvicidal, Swartzia polyphylla

JOURNAL FREE ACCESS

2006 Volume 54 Issue 2 Pages 278-279

DOI https://doi.org/10.1248/cpb.54.278

Details

Abstract

The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.

Corresponding author

Register with J-STAGE for free!