Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Quantitative Determination of Jatrophone in “Cachaça” Prepared with Jatropha elliptica
Rosenei Louzada BrumClaudia Andréa Lima CardosoNeli Kika HondaMaxwell Parrela AndreuLuiz Leonardo de Souza Viana
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2006 年 54 巻 5 号 p. 754-757

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A method for sample preparation and analysis by high performance liquid chromatography with UV detection (HPLC-UV) was developed for analysis of jatrophone in “cachaça” prepared with Jatropha elliptica, administered orally, employed in Brazil for the treatment of venomous snake bites. The linearity, accuracy, precision of the procedure was evaluated. Analytical curve for jatrophone was linear in the range of 16.24—81.20 μg ml−1. The recovery of the jatrophone in the samples analyzed was 98.99—99.89%. The percent coefficient of variation for the quantitative analysis of the “cachaça” in the analyses was under 2%.
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© 2006 The Pharmaceutical Society of Japan
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