2006 年 54 巻 7 号 p. 927-930
The transformation of physalin H (1) with Rhizopus stolonifer and Cunninghamella elegans has afforded two new physalins, 6,7-dehydrophysalin H (2) and 6-deoxyphysalin H (3), along with a known isophysalin B (4). Their structures were elucidated by spectroscopic analysis. All of these compounds have shown potent leishmanicidal activity with IC50 values in the range of 6.03—13.80 μM.