Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Cytotoxic Arylnaphthalene Lignans from Phyllanthus oligospermus
Shwu-Jen WuTian-Shung Wu
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2006 Volume 54 Issue 8 Pages 1223-1225

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Abstract
Three new arylnaphthalene lignans, namely phyllanthusmins A—C, together with nine known compounds were isolated and characterized from the stems and roots of Phyllanthus oligospermus by a bioassay-guided purification. The structures of the new compounds were elucidated by means of spectroscopic data interpretation. Among them, phyllanthusminA displayed significant cytotoxicity against KB and P-388 cancer cell lines.
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© 2006 The Pharmaceutical Society of Japan
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